| Owner | Public |
|---|---|
| URN | urn:agi-Expression:inout-urn:agi-cas:5300-03-8:out-urn:agi-llid:5465::positive |
| Entities | 9-cis-retinoic acid --+> PPARA |
| References | 6 |
| Connectivity | 2 |
| Effect | positive |
| CellLineName | COS I |
|---|---|
| Journal | Eur. J. Biochem |
| Journal Reference | v267 i13 p4063 (2000) |
| Journal Link | http://www.ejbiochem.org/cgi/content/full/267/13/4063 |
| MedLine Reference | 10866807:1026 |
| Sentence | However, stimulation of PPARalpha and all RXRs by clofibric acid and 9- cis -retinoic acid was observed in transient transfection assays. |
| Organism | Mus musculus |
|---|---|
| Journal | J. Biol. Chem |
| Journal Reference | v278 i7 p4467 (2003) |
| Journal Link | http://www.jbc.org/cgi/content/full/278/7/4467 |
| Organ | liver |
| MedLine Reference | 12482853:1036 |
| Sentence | A heterodimer of PPAR and RXR binds to PPREs located in upstream regulatory regions of various target genes and the RXR ligand, 9- cis -retinoic acid, increases PPAR/RXR transcriptional activity ( 4 ). |
| Organism | Rattus norvegicus |
|---|---|
| Organ | liver |
| MedLine Reference | 8389594:3 |
| Sentence | We show here that the retinoid X receptor (RXR) is required for PPAR to bind to the PPRE and that the RXR ligand, 9-cis retinoic acid, enhances PPAR action. |
| Organism | Rattus norvegicus |
|---|---|
| Organ | liver |
| MedLine Reference | 8240670:3 |
| Sentence | We show here that the retinoid X receptor (RXR) is required for PPAR to bind to the PPRE, and that the RXR ligand, 9-cis retinoic acid, enhances PPAR action. |
| Organism | Rattus norvegicus |
|---|---|
| Organ | jejunal |
| MedLine Reference | 7643237:5 |
| Sentence | Transcripts of both retinoid X receptor alpha and peroxisome proliferator-activated receptor (PPAR), which are thought to interact as a heterodimer with the cis-element located in the CRBP II promoter and to be activated by 9-cis retinoic acid and long-chain fatty acids, respectively, were constitutively expressed in the rat jejunum.(ABSTRACT TRUNCATED AT 250 WORDS) |
| CellLineName | THP I |
|---|---|
| Journal | ATVB |
| Journal Reference | v19 i9 p2105 (1999) |
| Journal Link | http://atvb.ahajournals.org/cgi/content/full/19/9/2105 |
| MedLine Reference | 10479651:1012 |
| Sentence | Expression of PPAR , a heterodimer partner of RXR, is also markedly induced by RA in THP-1 cells. |