| Transport Type | unknown |
|---|---|
| Owner | Public |
| URN | urn:agi-MolTransport:inout-urn:agi-llid:5465:out-urn:agi-cas:50-99-7::unknown |
| Entities | glucose <--- PPARA |
| References | 7 |
| Connectivity | 2 |
| Effect | unknown |
| Organism | Rattus norvegicus |
|---|---|
| MedLine Reference | 12600885:1105 |
| CellType | cardiomyocyte |
| Sentence | At concentrations of 10 A?Aµmol/L, these PPAR agonists were previously shown to be effective and isoform specific in other cell types. 6A?A?A?8 Cardiomyocytes As shown in Figure 4 , none of the PPAR ligands significantly affected the expression of genes involved in glucose uptake (GLUT4) and metabolism (HKII). |
| Journal | Circulation Res |
| Journal Reference | v92 i5 p518 (2003) |
| Journal Link | http://circres.ahajournals.org/cgi/content/full/92/5/518 |
| Tissue | skeletal muscle |
|---|---|
| Organism | Rattus norvegicus |
| MedLine Reference | 11334413:1316 |
| Sentence | It is also possible that the thiazolidinediones activate an alternative signal transduction pathway and increase glucose uptake through PPAR- A?A?A?independent mechanisms in skeletal muscle. |
| Journal | Diabetes |
| Journal Reference | v50 i5 p1093 (2001) |
| Journal Link | http://diabetes.diabetesjournals.org/cgi/content/full/50/5/1093 |
| Organism | Mus musculus |
|---|---|
| MedLine Reference | 12086932:1177 |
| CellType | adipocyte |
| Sentence | Furthermore, we carried out glucose transport assay to assess the effects of the alterations of protein expressions induced by PPAR- - C in mature 3T3-L1 adipocytes. |
| Journal | Diabetes |
| Journal Reference | v51 i7 p2045 (2002) |
| Journal Link | http://diabetes.diabetesjournals.org/cgi/content/full/51/7/2045 |
| CellLineName | 3T3 L1 |
| Organism | Mus musculus |
|---|---|
| Organ | heart |
| MedLine Reference | 11734553:1198 |
| Sentence | To determine whether PPARalpha has any direct effects on glucose transport, GLUT1 and GLUT4 levels were measured in the PPARalpha (-/-) and PPARalpha (+/+) hearts. |
| Journal | J. Biol. Chem |
| Journal Reference | v277 i6 p4098 (2002) |
| Journal Link | http://www.jbc.org/cgi/content/full/277/6/4098 |
| Organism | Rattus norvegicus |
|---|---|
| Organ | heart |
| MedLine Reference | 14563825:1228 |
| Sentence | Furthermore, mice with cardiac-restricted overexpression of PPARalpha showed activation of cardiac PPARalpha regulatory pathways that resulted in reciprocal repression of glucose uptake and utilization pathways. |
| Journal | Lipid Res |
| Journal Reference | v45 i1 p113 (2004) |
| Journal Link | http://www.jlr.org/cgi/content/full/45/1/113 |
| Organism | Mus musculus |
|---|---|
| MedLine Reference | 10976920:1104 |
| CellType | adipocyte |
| Sentence | PPAR agonists increase glucose uptake in 3T3-L1 adipocytes ( 19 ). |
| Journal | Mol. Endocrin |
| Journal Reference | v14 i9 p1425 (2000) |
| Journal Link | http://mend.endojournals.org/cgi/content/full/14/9/1425 |
| CellLineName | 3T3 L1 |
| Tissue | endocrine |
|---|---|
| Organism | Mus musculus |
| MedLine Reference | 11579205:1002 |
| CellType | adipocyte |
| Sentence | Alert me when: new articles cite this article Download to Citation Manager Molecular Endocrinology 15 (10): 1729-1738 Copyright A?A© 2001 by The Endocrine Society Potentiation of Glucose Uptake in 3T3-L1 Adipocytes by PPAR Agonists Is Maintained in Cells Expressing a PPAR Dominant-Negative Mutant: Evidence for Selectivity in the Downstream Responses to PPAR Activation Claire Nugent , Johannes B. |
| Journal | Mol. Endocrin |
| Journal Reference | v15 i10 p1729 (2001) |
| Journal Link | http://mend.endojournals.org/cgi/content/full/15/10/1729 |
| CellLineName | 3T3 L1 |