Protein : ETS1

Name ETS1
Description v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
Owner Public
URN urn:agi-llid:2113
Connectivity 111
Notes SUMMARY: activates transcription of cyclin-dependent kinase inhibitor p21WAF1/Cip1; plays a role in inhibition of apoptosis [RGD]
Hugo ID 3488

Microarray ID l20681_at
1368851_at
l20682mrna#1_g_at
rc_ai175900_g_at
A_43_P11462
A_51_P329038
A_51_P329043
A_52_P232830
J04101
214447_at
57073_at
1555355_a_at
A_23_P329212
A_23_P127525
A_14_P118575
A_14_P137920
A_14_P133647
A_14_P124986
A_14_P130059
A_24_P751074
B19
OH7934
R216
OR0375
224833_at
1518_at
1977_s_at
J04101_at
A_14_P108589
RC_AA504110_at

GenBank ID CAG47050
CR542254
J04101
M11921
NC_000011
NM_005238
NP_005229
NT_033899
NT_086789
AAA63299
AAH10588
AAH13089
AAK61536
AAN38315
AAN38316
AAN38317
AAR00342
AAR87824
AK052146
AK076233
AK193097
AY035702
AY134610
AY134611
AY134612
AY134613
AY134614
AY134615
AY423850
AY512954
BAC34858
BAC36266
BC010588
BC013089
CAA37904
CAA39310
AAA21093
AAI01928
BC101927
L20681
L20682
NC_005107
NM_012555
NP_036687
NW_047799
P41156
M58482
NC_000075
NM_011808
NP_035938
NT_039472
P27577
X53953
X55787
51827915
6753781
6753782
347142
296023
729453
26345231
26345232
14714868
14714869
15341827
15341828
193191
193192
50870
50871
296022
34865068
6978818
6978819
404783
404781
404782
729454
16878229
12429427
54695773
54695774
54695775
54695776
34364658
34364659
24772207
49457501
49457502
182268
182269
452904
452905
29881
296642
29882
119641
51468697
41393580
4885219
51470736
182266
182267
7023001
33878994
P14921
S67063
X14798
L21901
AAA52409
AAA52410
AAB28747
AAH17314
AAV38259
AAV38260
AK001630
BC017314
BG035366
BT019452
BT019453
BX640634
CA407336
CAA32903
CAA32904
CAE45783

Chromosome position 11q23.3
8q21
9 15.0 cM

GO ID 0000004
0003700
0003702
0005554
0005634
0006350
0006355
0006366
0006955
0008285
0008372
0016563
0000074
0003677
0006916

Alias AI448617
C-ets-1 protein
D230050P06
E26 avian leukemia oncogene 1, 5' domain
Ets1
Etsoncb
MGC18571
v-ets avian erythroblastosis virus E2 oncogene homolog 1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
v-ets erythroblastosis virus E26 oncogene homolog 1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
AI196000
hypothetical protein LOC270138
LOC270138
Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1
v-ets avian erythroblastosis virus E26 oncogene homolog I
v-ets avian erythroblastosis virus E2 oncogene homolog I
Avian erythroblastosis virus E26 (v-ets) oncogene homolog I
Ets I
expressed sequence AI196000
p42Ets-1
p51Ets-1
hypothetical protein D230050P06
v-ets erythroblastosis virus E26 oncogene homolog I
C-ets-1 proteins
Etsoncbs
ets avian erythroblastosis virus e2 oncogene homolog 1
ets avian erythroblastosis virus e2 oncogene homolog I
5' domain
binds to pea-3 (ets-1) sites in promotor regions
ets protein

Organism Rattus norvegicus
Homo sapiens
Mus musculus

MedLine Reference 2187191
7753825
12740370

LocusLink ID 23871
102453
2113
270138
330916
24356
102517

FunctionalClass RNA polymerase II transcription factor
molecular function unknown
transcription factor
DNA binding
transcriptional activator

RGD ID 2583

Hugo Symbol ETS1

Unigene ID Mm.292415
Rn.88756
Hs.369438

GO Cellular Component cellular component unknown
nucleus

Cell Localization Nucleus

Pathway ICAM1 -> ETS1 signalling pathway
KDR -> ETS1 signalling pathway
MET -> ETS1 signalling pathway
AGT-LRP2
EGF-ERBB2
EGF-ERBB3
EGF-ERBB4
EGF-LRP8
EGF-NGFR
FGF2-CD44
FGF2-FGFR1
FGF2-FGFR2
FGF2-FGFR3
FGF2-GPC1
FGF2-TGFBR3
HGF-CD44
HGF-FGFR2
HGF-IL6R
HGF-MET
PDGFA-PDGFRB
SPP1-CD44
SPP1-ITGAV
TGFB1-ACVR1
TGFB1-ACVR1B
TGFB1-ACVR2
TGFB1-ACVR2B
TGFB1-ACVRL1
TGFB1-BMPR1B
TGFB1-CD44
TGFB1-IGF2R
TGFB1-IL6R
TGFB1-M6PR
TGFB1-SELE
TGFB1-SELL
TGFB1-TGFBR1
TGFB1-TGFBR2
TGFB1-TGFBR3
TNF-IL15RA
TNF-NGFR
TNF-TNFRSF1B
VEGF-CD44
VEGF-EGFR
VEGF-FLT1
VEGF-FLT4
VEGF-GPC1
VEGF-IL1R1
VEGF-KDR
DuPont 4
PPAR all
PPARalpha
COUP-TF

GO Biological Process anti-apoptosis
regulation of progression through cell cycle
biological process unknown
immune response
negative regulation of cell proliferation
regulation of transcription, DNA-dependent
transcription
transcription from RNA polymerase II promoter
regulation of cell cycle
transcription from Pol II promoter

Group Transcription factors

MGI ID 95455

Swiss-Prot Accession P14921

OMIM ID 164720

Source Curated