| Owner | Public |
|---|---|
| URN | urn:agi-Binding:inout-urn:agi-llid:9612:inout-urn:agi-llid:5467: |
| Entities | NCOR2 ---- PPARD |
| References | 4 |
| Connectivity | 2 |
| Journal | J. Biol. Chem |
|---|---|
| Journal Reference | v276 i5 p3175 (2001) |
| Journal Link | http://www.jbc.org/cgi/content/full/276/5/3175 |
| MedLine Reference | 11069900:1269 |
| Sentence | PPARalpha and PPARgamma have been shown to interact with the SMRT ( 26 , 55 ) and the N-CoR corepressors ( 56 , 57 ), and we have shown that N-CoR and SMRT interact strongly with PPARdelta and repress transactivation by PPARdelta in a ligand-independent manner. 2 Whether cAMP-dependent enhancement of PPARdelta-mediated transactivation proceeds via protein kinase A-dependent phosphorylation of PPARdelta, dissociation of corepressor complexes, recruitment of coactivators, or by other mechanism(s) is currently under investigation. |
| Organism | Mus musculus |
| Tissue | fat |
| Journal | PNAS |
|---|---|
| Journal Reference | v99 i5 p2613 (2002) |
| Journal Link | http://www.pnas.org/cgi/content/full/99/5/2613 |
| MedLine Reference | 11867749:1080 |
| Sentence | Results Discussion References PPARdelta Associates with SMRT, SHARP, and HDACs. |
| Organism | Mus musculus |
| MedLine Reference | 2825137878 |
|---|---|
| Sentence | PPAR-delta interacts with SMRT. This interaction was modelled on a demonstrated interaction between PPAR-delta and SMRT from unspecified sources |
| Source | Entrez Gene |
| Source | Entrez Gene |
|---|