| Name | NCOA2 |
|---|---|
| Description | nuclear receptor coactivator 2 |
| Owner | Public |
| URN | urn:agi-llid:10499 |
| Connectivity | 44 |
| Notes | SUMMARY: binds to nuclear receptor complex leading to coactivation [RGD] |
| Hugo ID | 7669 |
| Microarray ID | 1368937_at |
|---|---|
| rc_aa946543_at | |
| rc_aa946543_g_at | |
| A_43_P12695 | |
| A_51_P478593 | |
| A_65_P07874 | |
| 212867_at | |
| 205731_s_at | |
| 34313_at | |
| 34312_at | |
| 205732_s_at | |
| 215605_at | |
| RC_AA292711_at | |
| X97674_at | |
| rc_t77464_at | |
| A_23_P428999 | |
| A_14_P118150 | |
| A_14_P100412 | |
| A_14_P124420 | |
| A_14_P110663 | |
| A_23_P134875 | |
| OH4896 | |
| OR2714 | |
| RT171 |
| Chromosome position | 5q11 |
|---|---|
| 8q13.3 | |
| 1 1.0 cM |
| GO ID | 0000122 |
|---|---|
| 0004872 | |
| 0005102 | |
| 0005509 | |
| 0005515 | |
| 0005737 | |
| 0006350 | |
| 0016564 | |
| 0030374 | |
| 0030375 | |
| 0045449 | |
| 0045944 | |
| 0003713 | |
| 0004871 | |
| 0005634 | |
| 0006355 | |
| 0007165 | |
| 0030528 |
| Alias | SRC-2 |
|---|---|
| GNB:1853980 | |
| glucocorticoid receptor-interactive protein I | |
| glucocorticoid receptor-interactive protein-1 | |
| GNB:1877215 | |
| N-COA2 | |
| 9530095N19 | |
| D1Ertd433e | |
| glucocorticoid receptor-interacting protein-1 | |
| NCOA2 | |
| nuclear receptor coactivator 2 | |
| TIF2/GRIP-1 | |
| Transcriptional intermediary factor 2 | |
| GRIP1/TIF2 | |
| nuclear receptor coactivator II | |
| Transcriptional intermediary factor II | |
| glucocorticoid receptor-interacting protein I | |
| TIF2 | |
| MP14 | |
| DNA segment, Chr 1, ERATO Doi 433, expressed |
| Organism | Mus musculus |
|---|---|
| Homo sapiens | |
| Rattus norvegicus |
| MedLine Reference | 10381882 |
|---|---|
| 11675124 | |
| 8670870 | |
| 9430642 | |
| 12130539 | |
| 12466851 | |
| 15072553 | |
| 15383530 | |
| 8643509 | |
| 9742117 |
| LocusLink ID | 269104 |
|---|---|
| 52119 | |
| 17978 | |
| 83724 | |
| 10499 |
| FunctionalClass | calcium ion binding |
|---|---|
| ligand-dependent nuclear receptor transcription coactivator | |
| protein binding | |
| receptor | |
| receptor binding | |
| thyroid hormone receptor coactivator | |
| transcriptional repressor | |
| signal transducer | |
| transcription coactivator | |
| transcription regulator |
| RGD ID | 620108 |
|---|
| Hugo Symbol | NCOA2 |
|---|
| Unigene ID | Rn.49136 |
|---|---|
| Mm.2537 | |
| Hs.446678 |
| GO Cellular Component | cytoplasm |
|---|---|
| nucleus |
| Cell Localization | Nucleus |
|---|
| Pathway | TGFB1-ACVR1 |
|---|---|
| TGFB1-ACVR1B | |
| TGFB1-ACVR2 | |
| TGFB1-ACVR2B | |
| TGFB1-ACVRL1 | |
| TGFB1-BMPR1B | |
| TGFB1-CD44 | |
| TGFB1-IGF2R | |
| TGFB1-IL6R | |
| TGFB1-M6PR | |
| TGFB1-SELE | |
| TGFB1-SELL | |
| TGFB1-TGFBR1 | |
| TGFB1-TGFBR2 | |
| TGFB1-TGFBR3 | |
| TNF-IL15RA | |
| TNF-NGFR | |
| TNF-TNFRSF1B | |
| PPAR all | |
| PPARalpha | |
| PPARbeta | |
| CAR | |
| AR | |
| RXR | |
| ERbeta | |
| ERalpha | |
| GR | |
| LRH-1 | |
| NOR1 | |
| TR | |
| NR common regulators |
| GO Biological Process | negative regulation of transcription from RNA polymerase II promoter |
|---|---|
| positive regulation of transcription from RNA polymerase II promoter | |
| regulation of transcription | |
| transcription | |
| regulation of transcription, DNA-dependent | |
| signal transduction | |
| negative regulation of transcription from Pol II promoter |
| Group | Transcription factors |
|---|
| MGI ID | 1276533 |
|---|
| Swiss-Prot Accession | Q15596 |
|---|
| OMIM ID | 601993 |
|---|
| Source | Curated |
|---|