| Owner | Public |
|---|---|
| URN | urn:agi-Expression:inout-urn:agi-smol:PGJ2:out-urn:agi-llid:5468::positive |
| Entities | PPARG <+-- PGJ2 |
| References | 4 |
| Connectivity | 2 |
| Effect | positive |
| Journal | Endocrin. Metabol |
|---|---|
| Journal Reference | v286 i4 pE560 (2004) |
| Tissue | islet |
| Journal Link | http://ajpendo.physiology.org/cgi/content/full/286/4/E560 |
| MedLine Reference | 14625208:1115 |
| Sentence | Moreover, both rosiglitazone and PGJ2 were able to completely prevent the suppression of PPARgamma2 mRNA expression induced by 1.0 mM FFA. |
| Organism | Rattus norvegicus |
|---|---|
| CellLineName | 3T3 L1 |
| Journal | Mol. Cancer Ther |
| Journal Reference | v3 i3 p247 (2004) |
| Journal Link | http://mct.aacrjournals.org/cgi/content/full/3/3/247 |
| MedLine Reference | 15026545:1171 |
| Sentence | Thus, DIM-C-pPhCF3, like PGJ2 and other synthetic PPARgamma agonists, induced PPARgamma-dependent differentiation in 3T3-L1 cells. |
| Organism | Rattus norvegicus |
|---|---|
| Journal | Gastr. Liver Phys |
| Journal Reference | v285 i1 pG20 (2003) |
| Journal Link | http://ajpgi.physiology.org/cgi/content/full/285/1/G20 |
| MedLine Reference | 12660143:1226 |
| Sentence | PGJ2 alone at 5 and 10 AµM, however, led to relatively smaller increases in luciferase activity by 150 and 190%, respectively, suggesting that PGJ2 might only activate endogenous PPAR-gamma expressed at a relatively low level in activated HSC. |
| CellLineName | ec |
|---|---|
| Organ | umbilical vein |
| MedLine Reference | 14971050:6 |
| Sentence | EMSA demonstrated an activation of PPARgamma by PGJ2 and rosiglitazone. |