| Entities | PPARG ---- CEBPA |
|---|---|
| References | 44 |
| Connectivity | 2 |
| Effect | positive |
| Owner | Public |
| URN | urn:agi-PromoterBinding:inout-urn:agi-llid:5468:inout-urn:agi-llid:1050::positive |
| Journal | J. Biol. Chem |
|---|---|
| Journal Reference | v278 i18 p15874 (2003) |
| Journal Link | http://www.jbc.org/cgi/content/full/278/18/15874 |
| MedLine Reference | 12606546:1102 |
| Sentence | INTRODUCTION EXPERIMENTAL PROCEDURES RESULTS DISCUSSION REFERENCES NFAT Cooperates with C / EBP to Increase PPARgamma2 Gene Transcription-- We demonstrated previously ( 7 ) that NFAT increases PPARgamma2 gene expression. |
| Tissue | fat |
|---|---|
| Organ | liver |
| Journal | J. Biol. Chem |
| Journal Reference | v278 i39 p37672 (2003) |
| Journal Link | http://www.jbc.org/cgi/content/full/278/39/37672 |
| MedLine Reference | 12821652:1207 |
| Sentence | C/EBPbeta and C/EBPdelta induce the expression of PPARgamma ( 9 , 10 ) via two C/EBP binding sites in the promoter of PPARgamma2 ( 38 , 47 ). |
| Organism | Rattus norvegicus |
| CellLineName | 3T3 L1 |
|---|---|
| Journal | J. Biol. Chem |
| Journal Reference | v279 i21 p21740 (2004) |
| Journal Link | http://www.jbc.org/cgi/content/full/279/21/21740 |
| MedLine Reference | 15024020:1184 |
| Sentence | Both C/EBPbeta and C/EBPdelta are essential in eliciting the expression of PPARgamma, which in turn leads to the induction of the expression of C/EBPalpha ( 10 , 37 , 38 ). |
| Organism | Rattus norvegicus |
| CellType | fibroblast |
|---|---|
| CellLineName | NIH 3T3 |
| Journal | J. Biol. Chem |
| Journal Reference | v279 i39 p40946 (2004) |
| Journal Link | http://www.jbc.org/cgi/content/full/279/39/40946 |
| MedLine Reference | 15258146:1033 |
| Sentence | Similarly, cells lacking C/EBPalpha have reduced adipogenic potential and expression of PPARgamma2 ( 12 ). |
| Organism | Mus musculus |
| CellLineName | C3H 10T1/2 |
|---|---|
| MedLine Reference | 11279134:3 |
| Sentence | In this regard, we also show that induction of C/EBPalpha gene expression by troglitazone in C3H10T1/2 cells ectopically expressing PPARgamma occurs in the absence of ongoing protein synthesis, suggesting a direct transactivation of the C/EBPalpha gene by PPARgamma. |
| Organism | Mus musculus |
| CellType | adipocyte |
|---|---|
| MedLine Reference | 15649418:5 |
| Sentence | Cells expressing both PPARgamma and C/EBPalpha showed more robust phenotype of adipocytes than the cells expressing PPARgamma alone. |
| Organism | Mus musculus |
| CellType | adipocyte |
|---|---|
| CellLineName | 3T3 L1 |
| Journal | Mol. Cell. Biol |
| Journal Reference | v22 i16 p5989 (2002) |
| Journal Link | http://mcb.asm.org/cgi/content/full/22/16/5989 |
| MedLine Reference | 12138207:1036 |
| Sentence | C/EBPA?A? and C/EBP mediate the transcriptional activation of peroxisome proliferator-activated receptor gamma (PPAR ) and C/EBP . |
| Organism | Mus musculus |
| CellType | fibroblast |
|---|---|
| CellLineName | NIH 3T3 |
| Journal | Mol. Cell. Biol |
| Journal Reference | v24 i19 p8671 (2004) |
| Journal Link | http://mcb.asm.org/cgi/content/full/24/19/8671 |
| MedLine Reference | 15367685:1203 |
| Sentence | Figure 7 shows the constitutive expression of PPARgamma2 in both cell lines (CalphaA? and Calpha+) and the absence of C/EBPalpha in the CalphaA? cell line. |
| Organism | Mus musculus |
| CellType | macrophage |
|---|---|
| Journal | Lipid Res |
| Journal Reference | v44 i10 p1877 (2003) |
| Journal Link | http://www.jlr.org/cgi/content/full/44/10/1877 |
| MedLine Reference | 12867536:1202 |
| Sentence | After 5 days, all treatments but insulin alone increased C/EBPalpha expression ( Fig. 9B ), and all but dexamethasone increased PPARgamma expression. |
| Organism | Mus musculus |
| Tissue | fat |
|---|---|
| Journal | J. Biol. Chem |
| Journal Reference | v272 i34 p21473 (1997) |
| Journal Link | http://www.jbc.org/cgi/content/full/272/34/21473 |
| MedLine Reference | 9261165:1118 |
| Sentence | Ectopic C/EBPalpha induces expression of PPARgamma. |
| Organism | Mus musculus |
| Journal | Mol. Cell. Biol |
|---|---|
| Journal Reference | v24 i11 p4651 (2004) |
| Journal Link | http://mcb.asm.org/cgi/content/full/24/11/4651 |
| MedLine Reference | 15143161:1174 |
| CellType | adipocyte |
|---|---|
| Journal | Cell Sci |
| Journal Reference | v115 i6 p1203 (1997) |
| Journal Link | http://jcs.biologists.org/cgi/content/full/115/6/1203 |
| MedLine Reference | 11884519:1238 |
| Organism | Mus musculus |
| CellType | adipocyte |
|---|---|
| Journal | Cell Sci |
| Journal Reference | v115 i18 p3601 (1997) |
| Journal Link | http://jcs.biologists.org/cgi/content/full/115/18/3601 |
| MedLine Reference | 12186946:1135 |
| Organism | Mus musculus |
| CellType | adipocyte |
|---|---|
| MedLine Reference | 9032283:2 |
| Organism | Mus musculus |
| CellLineName | UMR 106 |
|---|---|
| MedLine Reference | 9367890:2 |
| Organism | Mus musculus |
| CellLineName | NIH 3T3 |
|---|---|
| MedLine Reference | 10842659:6 |
| Organism | Mus musculus |
| MedLine Reference | 10862621:8 |
|---|---|
| Organism | Mus musculus |
| CellLineName | C3H 10T1/2 |
|---|---|
| Tissue | mesenchyma |
| MedLine Reference | 12925529:9 |
| Organism | Mus musculus |
| CellType | adipocyte |
|---|---|
| MedLine Reference | 15110775:6 |
| Organism | Mus musculus |
| CellType | adipocyte |
|---|---|
| MedLine Reference | 15158467:6 |
| Organism | Mus musculus |
| CellType | adipocyte |
|---|---|
| CellLineName | 3T3 L1 |
| MedLine Reference | 15664998:6 |
| Journal | Mol. Cell. Biol |
|---|---|
| Journal Reference | v21 i1 p319 (2001) |
| Journal Link | http://mcb.asm.org/cgi/content/full/21/1/319 |
| MedLine Reference | 11113206:1268 |
| Organism | Mus musculus |
| Organ | gastric |
|---|---|
| Journal | Reg.Int.Comp.Phys |
| Journal Reference | v282 i5 pR1286 (2002) |
| Journal Link | http://ajpregu.physiology.org/cgi/content/full/282/5/R1286 |
| MedLine Reference | 11959668:1160 |
| Organism | Mus musculus |
| CellLineName | NIH 3T3 |
|---|---|
| Journal | Endocrin. Metabol |
| Journal Reference | v279 i4 pE893 (2000) |
| Journal Link | http://ajpendo.physiology.org/cgi/content/full/279/4/E893 |
| MedLine Reference | 11001773:1037 |
| Organism | Rattus norvegicus |
| Tissue | bone |
|---|---|
| Journal | Endocrin. Metabol |
| Journal Reference | v286 i5 pE686 (2004) |
| Journal Link | http://ajpendo.physiology.org/cgi/content/full/286/5/E686 |
| MedLine Reference | 15102615:1181 |
| Organism | Mus musculus |
| CellType | adipocyte |
|---|---|
| CellLineName | 3T3 L1 |
| Journal | J. Biol. Chem |
| Journal Reference | v274 i12 p7946 (1999) |
| Journal Link | http://www.jbc.org/cgi/content/full/274/12/7946 |
| MedLine Reference | 10075691:1138 |
| Organism | Mus musculus |
| CellType | adipocyte |
|---|---|
| Journal | J. Biol. Chem |
| Journal Reference | v277 i51 p49776 (2002) |
| Journal Link | http://www.jbc.org/cgi/content/full/277/51/49776 |
| MedLine Reference | 12351639:1033 |
| Organism | Mus musculus |
| CellLineName | NIH 3T3 |
|---|---|
| Journal | J. Biol. Chem |
| Journal Reference | v278 i11 p9609 (2003) |
| Journal Link | http://www.jbc.org/cgi/content/full/278/11/9609 |
| MedLine Reference | 12524424:1309 |
| Organism | Mus musculus |
| Journal | J. Biol. Chem |
|---|---|
| Journal Reference | v279 i18 p18851 (2004) |
| Journal Link | http://www.jbc.org/cgi/content/full/279/18/18851 |
| MedLine Reference | 14985358:1277 |
| Organism | Mus musculus |
| CellType | fibroblast |
|---|---|
| Journal | J. Biol. Chem |
| Journal Reference | v279 i41 p42453 (2004) |
| Journal Link | http://www.jbc.org/cgi/content/full/279/41/42453 |
| MedLine Reference | 15277530:1283 |
| Organism | Mus musculus |
| CellType | adipocyte |
|---|---|
| Journal | J. Biol. Chem |
| Journal Reference | v272 i9 p5367 (1997) |
| Journal Link | http://www.jbc.org/cgi/content/full/272/9/5367 |
| MedLine Reference | 9102400:1129 |
| Organism | Mus musculus |
| CellLineName | 3T3 L1 |
|---|---|
| Journal | Mol. Cell. Biol |
| Journal Reference | v24 i8 p3505 (2004) |
| Journal Link | http://mcb.asm.org/cgi/content/full/24/8/3505 |
| MedLine Reference | 15060169:1139 |
| Organism | Mus musculus |
| Journal | Cell |
|---|---|
| Journal Reference | v87 i3 p377 (1996) |
| Journal Link | http://www.cell.com/cgi/content/full/87/3/377 |
| MedLine Reference | 4228051198 |
| CellType | fibroblast |
|---|---|
| Tissue | egg |
| Journal | Cell |
| Journal Reference | v99 i3 p239 (1999) |
| Journal Link | http://www.cell.com/cgi/content/full/99/3/239 |
| MedLine Reference | 2832201704 |
| Tissue | fat |
|---|---|
| Journal | J. Biol. Chem |
| Journal Reference | v278 i17 p15279 (2003) |
| Journal Link | http://www.jbc.org/cgi/content/full/278/17/15279 |
| MedLine Reference | 12578843:1215 |
| Organism | Mus musculus |
| CellType | adipocyte |
|---|---|
| Journal | Cell |
| Journal Reference | v87 i3 p377 (1996) |
| Journal Link | http://www.cell.com/cgi/content/full/87/3/377 |
| MedLine Reference | 4110956376 |
| Tissue | fat |
|---|---|
| Journal | Cell |
| Journal Reference | v99 i3 p239 (1999) |
| Journal Link | http://www.cell.com/cgi/content/full/99/3/239 |
| MedLine Reference | 2670796795 |
| CellType | adipocyte |
|---|---|
| Journal | Genes & Dev |
| Journal Reference | v16 i1 p1 (2002) |
| Journal Link | http://www.genesdev.org/cgi/content/full/16/1/1 |
| MedLine Reference | 11782439:1065 |
| CellType | fibroblast |
|---|---|
| Tissue | fat |
| Journal | Genes & Dev |
| Journal Reference | v16 i1 p22 (2002) |
| Journal Link | http://www.genesdev.org/cgi/content/full/16/1/22 |
| MedLine Reference | 11782441:1096 |
| Organism | Mus musculus |
| CellType | fibroblast |
|---|---|
| Journal | J. Biol. Chem |
| Journal Reference | v274 i31 p21920 (1999) |
| Journal Link | http://www.jbc.org/cgi/content/full/274/31/21920 |
| MedLine Reference | 10419513:1213 |
| Organism | Mus musculus |
| CellType | adipocyte |
|---|---|
| Journal | J. Biol. Chem |
| Journal Reference | v274 i35 p24965 (1999) |
| Journal Link | http://www.jbc.org/cgi/content/full/274/35/24965 |
| MedLine Reference | 10455174:1025 |
| Organism | Mus musculus |
| CellType | adipocyte |
|---|---|
| Journal | J. Biol. Chem |
| Journal Reference | v276 i30 p28098 (2001) |
| Journal Link | http://www.jbc.org/cgi/content/full/276/30/28098 |
| MedLine Reference | 11356826:1215 |
| Organism | Mus musculus |
| Tissue | fat |
|---|---|
| Organ | heart |
| Journal | J. Biol. Chem |
| Journal Reference | v277 i30 p26808 (2002) |
| Journal Link | http://www.jbc.org/cgi/content/full/277/30/26808 |
| MedLine Reference | 12011097:1025 |
| CellType | adipocyte |
|---|---|
| Journal | J. Biol. Chem |
| Journal Reference | v278 i4 p2581 (2003) |
| Journal Link | http://www.jbc.org/cgi/content/full/278/4/2581 |
| MedLine Reference | 12426306:1163 |
| Organism | Mus musculus |