| Entities | PPARG ---- GCG |
|---|---|
| References | 1 |
| Connectivity | 2 |
| Effect | unknown |
| Owner | Public |
| URN | urn:agi-PromoterBinding:inout-urn:agi-llid:5468:inout-urn:agi-llid:2641::unknown |
| Tissue | islet |
|---|---|
| Organ | pancreas |
| Journal | J. Biol. Chem |
| Journal Reference | v277 i3 p1941 (2002) |
| Journal Link | http://www.jbc.org/cgi/content/full/277/3/1941 |
| MedLine Reference | 11707457:1060 |
| Sentence | Mapping studies and the use of GAL4 fusion proteins indicate that PPARgamma represses in a ligand-dependent but DNA binding-independent manner transactivation by the paired domain-containing transcription factor Pax6 leading to inhibition of glucagon gene transcription. |