| Entities | UGT1A9 ---- PPARG |
|---|---|
| References | 1 |
| Connectivity | 2 |
| Effect | positive |
| Owner | Public |
| URN | urn:agi-PromoterBinding:inout-urn:agi-llid:5468:inout-urn:agi-llid:54600::positive |
| CellType | hepatocyte |
|---|---|
| CellLineName | HepG 2 |
| Journal | J. Biol. Chem |
| Journal Reference | v278 i16 p13975 (2003) |
| Journal Link | http://www.jbc.org/cgi/content/full/278/16/13975 |
| MedLine Reference | 12582161:1122 |
| Sentence | PPAR alpha induces human UGT1A9 mRNA in hepatocytes and HepG2 cells, and PPAR gamma stimulates murine UGT1A9 expression in 3T3-L1 adipocytes. a , primary human hepatocytes were treated with Me2SO (vehicle) or fenofibric acid (250 Aµ M ) for 6, 12, or 24 h. b , HepG2 cells were infected with Ad-PPARalpha or Ad-GFP for 3 h and subsequently stimulated for 24 h with vehicle or Wy14643 (50 Aµ M ). c , 3T3-L1 adipocytes were treated or not with rosiglitazone (1 Aµ M ) for 24 h. |
| Organism | Mus musculus |