PromoterBinding :

Entities PPARG ---- SCARB1
References 3
Connectivity 2
Effect positive
Owner Public
URN urn:agi-PromoterBinding:inout-urn:agi-llid:949:inout-urn:agi-llid:5468::positive

CellType hepatocyte
Tissue endothelial
Organ liver
MedLine Reference 12763030:4
Sentence PPARgamma/RXR binds to a response element between -459 and -472 bp in the human SR-BI promoter.
Organism Rattus norvegicus

CellType macrophage
Journal Lipid Res
Journal Reference v45 i5 p889 (2004)
Journal Link http://www.jlr.org/cgi/content/full/45/5/889
MedLine Reference 14967816:1248
Sentence Finally, ligands of PPARalpha and PPARgamma upregulate SR-BI expression in human monocytes/macrophages in the atherosclerotic lesion of apolipoprotein E-null mice ( 42 ).
Organism Mus musculus

CellType macrophage
MedLine Reference 10821819:6
Sentence Activation of PPARalpha and PPARgamma resulted in the induction of CLA-1 protein expression in monocytes and in differentiated macrophages.
Organism Mus musculus