| Name | HMG1 |
|---|---|
| Description | high-mobility group box 1 |
| Owner | Public |
| URN | urn:agi-llid:3146 |
| Connectivity | 64 |
| Notes | SUMMARY: heparin binding protein that facilitates neurite outgrowth [RGD] |
| Hugo ID | 4983 |
| Microarray ID | m64986_at |
|---|---|
| A_43_P15527 | |
| A_51_P269553 | |
| A_51_P165822 | |
| A_51_P269554 | |
| 200679_x_at | |
| 214938_x_at | |
| 224734_at | |
| 224731_at | |
| 32220_at | |
| 59135_at | |
| 65806_at | |
| 67687_at | |
| 77082_at | |
| 200680_x_at | |
| D63874_at | |
| RC_AA205334_at | |
| RC_AA486201_s_at | |
| 56712_at | |
| 90071_r_at | |
| A_32_P462420 | |
| A_32_P134580 | |
| A_23_P99985 | |
| A_23_P162805 | |
| A_14_P125946 | |
| A_24_P801264 | |
| A_24_P169148 | |
| A_23_P99980 | |
| A_14_P130269 | |
| OR1109 | |
| OH2248 | |
| RG464 | |
| AH166 |
| Chromosome position | 16p11 |
|---|---|
| 5 83.0 cM | |
| 13q12 |
| GO ID | 0006810 |
|---|---|
| 0030235 | |
| 0000902 | |
| 0007399 | |
| 0000785 | |
| 0000793 | |
| 0005634 | |
| 0006268 | |
| 0006281 | |
| 0006288 | |
| 0006310 | |
| 0006325 | |
| 0006357 | |
| 0008134 | |
| 0008301 | |
| 0017055 | |
| 0008201 | |
| 0003677 | |
| 0005515 | |
| 0005615 | |
| 0005694 | |
| 0006323 | |
| 0006355 | |
| 0006809 |
| Alias | similar to high mobility group protein (Spalax ehrenbergi) |
|---|---|
| similar to HMG-L6 | |
| similar to High mobility group protein 1 (HMG-1) | |
| similar to nonhistone chromosomal protein HMG-1 - human | |
| similar to high mobility group 1 [Gallus gallus] | |
| HMG-1 | |
| dkfzp686a04236 | |
| Amphoterin | |
| high mobility group box 1 | |
| High mobility group protein HMG1 | |
| high-mobility group (nonhistone chromosomal) protein 1 | |
| high-mobility group protein 1 | |
| HMG3 | |
| HMGB1 | |
| HMG-L6 | |
| high mobility group protein (Spalax ehrenbergi) | |
| nonhistone chromosomal protein HMG-1 - human | |
| high mobility group box I | |
| high-mobility group (nonhistone chromosomal) protein I | |
| High mobility group protein 1 (HMG-1) | |
| SBP-1 | |
| Sulfoglucuronyl carbohydrate binding protein | |
| High mobility group protein HMG I | |
| HMGB I | |
| HMG I | |
| SBP I |
| Organism | Mus musculus |
|---|---|
| Rattus norvegicus | |
| Homo sapiens |
| MedLine Reference | 12198705 |
|---|---|
| 15140875 | |
| 1885601 | |
| 11246022 | |
| 11748232 | |
| 12925773 | |
| 8006019 | |
| 9600082 |
| LocusLink ID | 246364 |
|---|---|
| 25459 | |
| 15289 | |
| 3146 |
| FunctionalClass | DNA bending |
|---|---|
| transcription factor binding | |
| DNA binding | |
| heparin binding | |
| nitric-oxide synthase regulator | |
| protein binding |
| RGD ID | 2802 |
|---|
| Hugo Symbol | HMGB1 |
|---|
| Unigene ID | Rn.4121 |
|---|---|
| Mm.313345 | |
| Hs.475685 |
| GO Cellular Component | chromosome |
|---|---|
| extracellular space | |
| chromatin | |
| condensed chromosome | |
| nucleus |
| Cell Localization | Nucleus |
|---|
| Pathway | TLR2 -> HMG1 signalling pathway |
|---|---|
| TLR4 -> HMG1 signalling pathway | |
| AGER -> HMG1 signalling pathway | |
| IFNG-HLA-C | |
| IFNG-IFNGR1 | |
| IFNG-IFNGR2 | |
| IL1A-IL1R1 | |
| IL1A-IL1RAP | |
| IL1B-HLA-DRB1 | |
| IL1B-IL1R1 | |
| IL1B-IL1RAP | |
| IL1B-IL6R | |
| IL6-IL6R | |
| IL6-LIFR | |
| PLG-IGF2R | |
| TGFB1-ACVR1 | |
| TGFB1-ACVR1B | |
| TGFB1-ACVR2 | |
| TGFB1-ACVR2B | |
| TGFB1-ACVRL1 | |
| TGFB1-BMPR1B | |
| TGFB1-CD44 | |
| TGFB1-IGF2R | |
| TGFB1-IL6R | |
| TGFB1-M6PR | |
| TGFB1-SELE | |
| TGFB1-SELL | |
| TGFB1-TGFBR1 | |
| TGFB1-TGFBR2 | |
| TGFB1-TGFBR3 | |
| TNF-IL15RA | |
| TNF-NGFR | |
| TNF-TNFRSF1B | |
| PPAR all | |
| PPARgamma | |
| ERbeta | |
| ERalpha | |
| GR | |
| NR common regulators |
| GO Biological Process | regulation of transcription from Pol II promoter |
|---|---|
| DNA packaging | |
| nitric oxide biosynthesis | |
| regulation of transcription, DNA-dependent | |
| transport | |
| cellular morphogenesis | |
| neurogenesis | |
| DNA recombination | |
| DNA repair | |
| DNA unwinding | |
| base-excision repair, DNA ligation | |
| establishment and/or maintenance of chromatin architecture | |
| negative regulation of transcriptional preinitiation complex formation | |
| regulation of transcription from RNA polymerase II promoter |
| Group | Transcription factors |
|---|
| MGI ID | 96113 |
|---|
| Swiss-Prot Accession | P09429 |
|---|
| OMIM ID | 163905 |
|---|
| Source | Curated |
|---|