| Name | JUND |
|---|---|
| Description | jun D proto-oncogene |
| Owner | Public |
| URN | urn:agi-llid:3727 |
| Connectivity | 59 |
| Notes | The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. It has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternate translation initiation site usage results in the production of different isoforms. |
| Hugo ID | 6206 |
| Microarray ID | 1387762_s_at |
|---|---|
| d26307cds_at | |
| rc_ai231178_at | |
| A_43_P15517 | |
| 102364_at | |
| 1449117_at | |
| msa.21602.0_s_at | |
| msa.7608.0_s_at | |
| msa.869.0_f_at | |
| x15358_f_at | |
| A_51_P357744 | |
| X51346 | |
| 214326_x_at | |
| 229117_s_at | |
| 55676_r_at | |
| 203752_s_at | |
| 203751_x_at | |
| 1612_s_at | |
| 41483_s_at | |
| 41484_r_at | |
| X56681_s_at | |
| 75034_at | |
| rc_aa115508_f_at | |
| A_23_P365610 | |
| A_23_P142368 | |
| A_14_P138764 | |
| A_14_P108356 | |
| M161 | |
| R076 | |
| OR0241 | |
| 764 | |
| OH2094 |
| Chromosome position | 19p13.2 |
|---|---|
| 8 33.0 cM | |
| 16p14 |
| GO ID | 0000785 |
|---|---|
| 0003700 | |
| 0003702 | |
| 0005634 | |
| 0006350 | |
| 0006357 | |
| 0000074 | |
| 0003677 | |
| 0005622 | |
| 0006355 | |
| 0050875 |
| Alias | Transcription factor JUN-D |
|---|---|
| Jund I | |
| JunD-FL isoform | |
| MGC6245 | |
| MGC72300 | |
| Jund1 | |
| JunD-FL isoforms | |
| Jun D | |
| Jun D proto-oncogene | |
| Jun proto-oncogene related gene d1 | |
| JUND |
| Organism | Rattus norvegicus |
|---|---|
| Homo sapiens | |
| Mus musculus |
| MedLine Reference | 12220541 |
|---|---|
| 1903194 | |
| 12105216 |
| LocusLink ID | 16478 |
|---|---|
| 24518 | |
| 3727 |
| FunctionalClass | RNA polymerase II transcription factor |
|---|---|
| transcription factor | |
| DNA binding |
| RGD ID | 2945 |
|---|
| Hugo Symbol | JUND |
|---|
| Unigene ID | Rn.46225 |
|---|---|
| Hs.2780 | |
| Mm.1175 |
| KEGG pathway | MAPK signaling pathway |
|---|
| GO Cellular Component | chromatin |
|---|---|
| nucleus | |
| intracellular |
| Cell Localization | Nucleus |
|---|
| Pathway | CD19 -> JUND signalling pathway |
|---|---|
| TNFRSF5 -> JUND signalling pathway | |
| RET -> JUND signalling pathway | |
| CNTF-CNTFR | |
| CNTF-IL6ST | |
| CNTF-LIFR | |
| EGF-ERBB2 | |
| EGF-ERBB3 | |
| EGF-ERBB4 | |
| EGF-LRP8 | |
| EGF-NGFR | |
| FGF2-CD44 | |
| FGF2-FGFR1 | |
| FGF2-FGFR2 | |
| FGF2-FGFR3 | |
| FGF2-GPC1 | |
| FGF2-TGFBR3 | |
| HGF-CD44 | |
| HGF-FGFR2 | |
| HGF-IL6R | |
| HGF-MET | |
| IL15-IL15RA | |
| IL15-IL2RB | |
| IL15-IL2RG | |
| IL2-IL15RA | |
| IL2-IL2RA | |
| IL2-IL2RB | |
| IL2-IL4R | |
| IL6-IL6R | |
| IL6-IL6ST | |
| IL6-LIFR | |
| IL6-TNFRSF5 | |
| INS-EGFR | |
| INS-HLA-DRB1 | |
| INS-TFRC | |
| PGF-FLT1 | |
| PGF-KDR | |
| TGFB1-ACVR1 | |
| TGFB1-ACVR1B | |
| TGFB1-ACVR2 | |
| TGFB1-ACVR2B | |
| TGFB1-ACVRL1 | |
| TGFB1-BMPR1B | |
| TGFB1-CD44 | |
| TGFB1-IGF2R | |
| TGFB1-IL6R | |
| TGFB1-M6PR | |
| TGFB1-SELE | |
| TGFB1-SELL | |
| TGFB1-TGFBR1 | |
| TGFB1-TGFBR2 | |
| TGFB1-TGFBR3 | |
| TNF-IL15RA | |
| TNF-NGFR | |
| TNF-TNFRSF1B | |
| TNFSF11-TNFRSF11A | |
| TNFSF11-TNFRSF11B | |
| Volcano 2 | |
| PPAR all | |
| PPARgamma |
| GO Biological Process | regulation of transcription from Pol II promoter |
|---|---|
| regulation of cell cycle | |
| regulation of transcription from RNA polymerase II promoter | |
| transcription | |
| cellular physiological process | |
| regulation of progression through cell cycle | |
| regulation of transcription, DNA-dependent |
| Group | Transcription factors |
|---|---|
| New Group |
| MGI ID | 96648 |
|---|
| Swiss-Prot Accession | P17535 |
|---|
| OMIM ID | 165162 |
|---|
| Source | Curated |
|---|