| Name | SMARCD3 |
|---|---|
| Description | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| Owner | Public |
| URN | urn:agi-llid:6604 |
| Connectivity | 3 |
| Notes | The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. BAF60c represents a new coregulator that constitutes an important anchoring point by which the SWI/SNF complex is recruited to nuclear receptors and other transcription factors. SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. |
| Microarray ID | 1371665_at |
|---|---|
| rc_ai145891_at | |
| 107702_f_at | |
| 108488_at | |
| 108911_at | |
| 131683_f_at | |
| 135921_f_at | |
| 1418467_at | |
| 1453846_at | |
| 168558_f_at | |
| A_51_P423880 | |
| 231144_at | |
| 32565_at | |
| 80155_at | |
| 86404_at | |
| 204099_at | |
| 456_at | |
| U66619_at | |
| A_23_P122852 | |
| A_14_P120537 | |
| OH3071 | |
| AH322 |
| Chromosome position | 5 A3 |
|---|---|
| 4q11 | |
| 7q35-q36 |
| GO ID | 0003713 |
|---|---|
| 0005102 | |
| 0005654 | |
| 0006338 | |
| 0006350 | |
| 0006357 | |
| 0008134 | |
| 0016514 | |
| 0030528 | |
| 0035257 | |
| 0045893 | |
| 0005634 | |
| 0006355 | |
| 0008318 | |
| 0016568 | |
| 0018342 |
| Alias | chromatin remodeling complex BAF60C subunit |
|---|---|
| CRACD3 | |
| mammalian chromatin remodeling complex BRG1-associated factor 60C | |
| 1500001J14Rik | |
| SWI/SNF-related matrix-associated actin-dependent regulator of chromatin d3 | |
| CRACD3s | |
| 60kda brg-1/brm associated factor subunit c | |
| BAF60C | |
| SWI/SNF complex 60 kDa subunit C | |
| Smarcd3 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| MedLine Reference | 12466851 |
|---|---|
| 14701856 | |
| 8804307 |
| LocusLink ID | 66993 |
|---|---|
| 6604 | |
| 296732 | |
| 78383 |
| FunctionalClass | nuclear hormone receptor binding |
|---|---|
| receptor binding | |
| transcription coactivator | |
| transcription factor binding | |
| transcription regulator | |
| protein prenyltransferase |
| GO Cellular Component | SWI/SNF complex |
|---|---|
| nucleoplasm | |
| nucleus |
| Pathway | PPAR all |
|---|---|
| PPARgamma |
| GO Biological Process | chromatin remodeling |
|---|---|
| positive regulation of transcription, DNA-dependent | |
| regulation of transcription from RNA polymerase II promoter | |
| transcription | |
| chromatin modification | |
| protein prenylation | |
| regulation of transcription, DNA-dependent |
| Source | Curated |
|---|