| Name | FABP1 |
|---|---|
| Description | fatty acid binding protein 1, liver |
| Owner | Public |
| URN | urn:agi-llid:2168 |
| Connectivity | 11 |
| Notes | FABP1 encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP1 and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. Besides I-FABP, also L-FABP is a useful plasma marker for the detection of intestinal injury, especially in patients undergoing intestinal surgery. Evidence that FABP is a target for tamoxifen and that target proteins are implicated in cell lipid metabolism. |
| Microarray ID | 1369111_at |
|---|---|
| 38586_at | |
| 205892_s_at | |
| M10050_at | |
| A_23_P79562 | |
| A_14_P108653 | |
| H151 | |
| OH0896A | |
| R302 | |
| OR0483 | |
| v01235_at | |
| A_43_P15521 | |
| 102462_f_at | |
| 1417556_at | |
| 1448764_a_at | |
| 162342_at | |
| 94075_at | |
| aa591003_f_at | |
| msa.15669.0_f_at | |
| A_51_P487818 | |
| 214158_s_at | |
| 231693_at |
| Chromosome position | 6 30.0 cM |
|---|---|
| 2p11 | |
| 4q32 |
| GO ID | 0003682 |
|---|---|
| 0005215 | |
| 0005488 | |
| 0005504 | |
| 0007067 | |
| 0008284 | |
| 0005319 | |
| 0005737 | |
| 0006631 | |
| 0006810 | |
| 0007267 | |
| 0008289 | |
| 0009887 |
| Alias | Fabp I |
|---|---|
| L-FABP | |
| fatty-acid-binding protein | |
| mgc108756 | |
| Fabp1 | |
| Fabplg | |
| fatty acid binding protein 1 | |
| fatty acid binding protein 1, liver | |
| liver Fatty acid-binding protein | |
| MGC13855 | |
| RATFABPLG | |
| fatty acid binding protein I | |
| FABPL | |
| Fatty acid-binding protein, liver |
| Organism | Mus musculus |
|---|---|
| Homo sapiens | |
| Rattus norvegicus |
| MedLine Reference | 10191295 |
|---|---|
| 15522233 | |
| 3478711 | |
| 9250612 |
| LocusLink ID | 14080 |
|---|---|
| 24360 | |
| 54005 | |
| 2168 |
| FunctionalClass | binding |
|---|---|
| chromatin binding | |
| fatty acid binding | |
| transporter | |
| lipid binding | |
| lipid transporter |
| GO Cellular Component | cytoplasm |
|---|
| Cell Localization | Cytoplasm |
|---|
| Pathway | PPAR all |
|---|---|
| PPARgamma | |
| PPARalpha |
| GO Biological Process | cell-cell signaling |
|---|---|
| fatty acid metabolism | |
| organogenesis | |
| transport | |
| mitosis | |
| positive regulation of cell proliferation |
| Source | Curated |
|---|