| Name | CREBBP |
|---|---|
| Description | CREB binding protein |
| Owner | Public |
| URN | urn:agi-llid:1387 |
| Connectivity | 159 |
| Notes | SUMMARY: a transcriptional co-activator; has an important role in hormone-dependent female sexual behavior and long term memory [RGD] |
| Hugo ID | 2348 |
| Microarray ID | A_43_P13167 |
|---|---|
| 1387619_at | |
| 111958_at | |
| 1436983_at | |
| A_51_P448224 | |
| 228177_at | |
| 235858_at | |
| 33831_at | |
| 46099_at | |
| 85348_at | |
| 202160_at | |
| 211808_s_at | |
| U89355_at | |
| W24319_at | |
| 216362_at | |
| rc_aa609754_at | |
| rc_w89077_s_at | |
| A_23_P163850 | |
| A_14_P126635 | |
| OH1388 | |
| CA255 | |
| A_14_P109618 | |
| A_14_P115371 | |
| A_14_P100940 | |
| MA143 | |
| A_14_P118346 | |
| A_24_P342279 | |
| A_24_P322025 |
| Chromosome position | 16p13.3 |
|---|---|
| 16 A1 |
| GO ID | 0001666 |
|---|---|
| 0003700 | |
| 0003713 | |
| 0004402 | |
| 0008283 | |
| 0004871 | |
| 0005515 | |
| 0005634 | |
| 0005737 | |
| 0046872 | |
| 0006355 | |
| 0006461 | |
| 0007165 | |
| 0008270 | |
| 0016740 | |
| 0042592 | |
| 0000123 | |
| 0000940 | |
| 0003677 | |
| 0003712 | |
| 0005667 | |
| 0006350 | |
| 0016407 | |
| 0045449 | |
| 0045893 |
| Alias | CREBBP |
|---|---|
| similar to CREB-binding protein | |
| CBP_MOUSE | |
| histone acetyltransferase CBP | |
| Rubinstein-Taybi syndrome | |
| Creb binding (CBP) | |
| CBP | |
| RTS | |
| Creb binding protein (CBP) | |
| CREB binding protein | |
| CREB binding protein (Rubinstein-Taybi syndrome) | |
| CREB-binding protein | |
| Rubinstein-Taybi syndrome protein | |
| RSTS |
| Organism | Human |
|---|---|
| Rattus norvegicus | |
| Mus musculus | |
| Homo sapiens |
| MedLine Reference | 11796496 |
|---|---|
| 12477714 | |
| 15005629 | |
| 10428834 | |
| 15261140 | |
| 7913207 | |
| 8028671 | |
| 8684459 | |
| 11867645 | |
| 11963968 | |
| 12464179 | |
| 12496368 | |
| 14519686 | |
| 14716005 | |
| 15161102 | |
| 15464984 | |
| 15681609 | |
| 15752756 | |
| 9742083 |
| LocusLink ID | 547230 |
|---|---|
| 12914 | |
| 1387 | |
| 54244 | |
| 436331 | |
| 106441 |
| FunctionalClass | metal ion binding |
|---|---|
| protein binding | |
| signal transducer | |
| transcription coactivator | |
| transcription factor | |
| transferase | |
| zinc ion binding | |
| transcription cofactor | |
| DNA binding | |
| acetyltransferase | |
| histone acetyltransferase |
| RGD ID | 2401 |
|---|
| Hugo Symbol | CREBBP |
|---|
| Unigene ID | Hs.270804 |
|---|---|
| Mm.132238 | |
| Rn.108128 | |
| Hs.459759 |
| GO Cellular Component | histone acetyltransferase complex |
|---|---|
| outer kinetochore of condensed chromosome | |
| transcription factor complex | |
| cytoplasm | |
| nucleus |
| Cell Localization | Nucleus |
|---|
| Pathway | TGF-beta signaling |
|---|---|
| CD28 -> CREBBP signalling pathway | |
| FGFR1 -> CREBBP signalling pathway | |
| EGF-ERBB2 | |
| EGF-ERBB3 | |
| EGF-ERBB4 | |
| EGF-LRP8 | |
| EGF-NGFR | |
| IL6-IL6R | |
| IL6-IL6ST | |
| IL6-LIFR | |
| IL6-TNFRSF5 | |
| INS-EGFR | |
| INS-HLA-DRB1 | |
| INS-TFRC | |
| NGFB-NGFR | |
| NGFB-NTRK1 | |
| NGFB-NTRK2 | |
| NGFB-NTRK3 | |
| TGFB1-ACVR1 | |
| TGFB1-ACVR1B | |
| TGFB1-ACVR2 | |
| TGFB1-ACVR2B | |
| TGFB1-ACVRL1 | |
| TGFB1-BMPR1B | |
| TGFB1-CD44 | |
| TGFB1-IGF2R | |
| TGFB1-IL6R | |
| TGFB1-M6PR | |
| TGFB1-SELE | |
| TGFB1-SELL | |
| TGFB1-TGFBR1 | |
| TGFB1-TGFBR2 | |
| TGFB1-TGFBR3 | |
| PPAR all | |
| PPARgamma | |
| PPARalpha | |
| AR | |
| ERalpha | |
| GR | |
| HNF4a | |
| NR common regulators |
| GO Biological Process | cell proliferation |
|---|---|
| positive regulation of transcription, DNA-dependent | |
| regulation of transcription | |
| transcription | |
| homeostasis | |
| protein complex assembly | |
| regulation of transcription, DNA-dependent | |
| response to hypoxia | |
| signal transduction |
| Group | Transcription factors |
|---|
| EC Number | 2.3.1.48 |
|---|
| MGI ID | 1098280 |
|---|
| Swiss-Prot Accession | Q92793 |
|---|
| OMIM ID | 600140 |
|---|---|
| 180849 | |
| OMIM:600140 | |
| OMIM:180849 |
| Source | Curated |
|---|