Protein : OCLN

Name OCLN
Description occludin
Owner Public
URN urn:agi-llid:4950
Connectivity 28
Notes This gene encodes an integral membrane protein which is located at tight junctions. This protein may be involved in the formation and maintenance of the tight junction. The possibility of several alternatively spliced products has been suggested but the full nature of these products has not been described.
Hugo ID 8104

Microarray ID 1448873_at
92907_at
msa.2061.0_s_at
u49185_s_at
A_51_P486155
A_51_P486150
227492_at
38524_at
43530_at
209925_at
235937_at
N76904_at
rc_h94471_at
u19251_s_at
A_23_P92672
A_24_P102053
OH2416A
V189
MB806
AH151

GenBank ID 26335194
NT_086674
Q16625
U49184
U53823
26335195
1293543
1293544
3914209
51465008
9257230
4505487
51465022
17864890
17864891
20987417
20987418
54400343
54400344
1276978
1276979
1322281
1322282
3914196
51767945
31982140
6679162
12860264
12860265
26083449
AAC52515
AK019880
AK033532
AK042576
AK145798
BAB31900
BAC31298
BAE26656
NC_000079
NM_008756
NP_032782
NT_039590
Q61146
U49185
AAB00195
AAC50451
AAH29886
AAL47094
AF400630
BC029886
BK001650
DAA01837
NC_000005
NM_002538
NP_002529
NT_006713

Chromosome position 5q13.1
13 55.9 cM

GO ID 0005515
0016020
0005198
0005886
0005923
0006461
0016021

Alias Ocl
occludin
OCLN
tight junction protein occludin tm4 minus

Organism Mus musculus
Homo sapiens

MedLine Reference 11025210
11782481
12060405
12466851
14685273
10749869
8601611

LocusLink ID 18260
4950

FunctionalClass protein binding
structural molecule

Hugo Symbol OCLN

Unigene ID Hs.482439
Mm.4807

GO Cellular Component membrane
integral to membrane
plasma membrane
tight junction

Cell Localization Plasma membrane

Pathway CSF1-IL6R
CSF1-TNFRSF5
EGF-ERBB2
EGF-ERBB3
EGF-ERBB4
EGF-LRP8
EGF-NGFR
HGF-FGFR2
HGF-IL6R
IFNG-HLA-C
IFNG-IFNGR2
IL11-IL6R
IL1B-HLA-DRB1
TGFB1-ACVR1
TGFB1-ACVR1B
TGFB1-ACVR2
TGFB1-ACVR2B
TGFB1-ACVRL1
TGFB1-BMPR1B
TGFB1-CD44
TGFB1-IGF2R
TGFB1-IL6R
TGFB1-M6PR
TGFB1-SELE
TGFB1-SELL
TGFB1-TGFBR1
TGFB1-TGFBR2
TGFB1-TGFBR3
TNF-IL15RA
TNF-NGFR
TNFSF11-TNFRSF11B
VEGF-CD44
VEGF-GPC1
VEGF-IL1R1
PPAR all
PPARgamma

GO Biological Process protein complex assembly

Group Cytoskeleton

MGI ID 106183

Swiss-Prot Accession Q16625

OMIM ID 602876

Source Curated