| Name | NFE2L2 |
|---|---|
| Description | nuclear factor (erythroid-derived 2)-like 2 |
| Owner | Public |
| URN | urn:agi-llid:4780 |
| Connectivity | 42 |
| Notes | NFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human genes encoding basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other (Chan et al., 1995 [PubMed 7868116]).[supplied by OMIM] |
| Hugo ID | 7782 |
| Microarray ID | 76863_at |
|---|---|
| 201146_at | |
| 853_at | |
| S74017_at | |
| rc_h88359_s_at | |
| rc_t83573_s_at | |
| A_23_P5761 | |
| A_14_P112032 | |
| A_14_P130857 | |
| A_24_P936444 | |
| M446 | |
| OH2770 | |
| OR2011 | |
| RA0346 | |
| AH522 | |
| u70475_s_at | |
| A_51_P411271 | |
| 36235_at | |
| A_52_P396436 | |
| 64346_r_at | |
| 236213_at | |
| 1367826_at | |
| rc_ai043736_at | |
| rc_ai177161_at | |
| rc_ai177161_g_at | |
| A_42_P541213 | |
| A_43_P14931 | |
| 1416543_at | |
| 92562_at |
| Chromosome position | 2q31 |
|---|---|
| 3q23 | |
| 2 45.0 cM |
| GO ID | 0003677 |
|---|---|
| 0003700 | |
| 0004867 | |
| 0005634 | |
| 0006350 | |
| 0006355 | |
| 0006366 |
| Alias | NF-E2 related factor 2 |
|---|---|
| nuclear factor (erythroid-derived 2)-like 2 | |
| Nfe2l2 | |
| NFE2-related factor 2 | |
| NRF2 | |
| Nuclear factor erythroid 2 related factor 2 | |
| NF-E2 related factor II | |
| NFE2-related factor II |
| Organism | Mus musculus |
|---|---|
| Rattus norvegicus | |
| Homo sapiens |
| MedLine Reference | 12220541 |
|---|---|
| 7937919 |
| LocusLink ID | 98874 |
|---|---|
| 18024 | |
| 83619 | |
| 4780 |
| FunctionalClass | DNA binding |
|---|---|
| serine-type endopeptidase inhibitor | |
| transcription factor |
| RGD ID | 620360 |
|---|
| Hugo Symbol | NFE2L2 |
|---|
| Unigene ID | Hs.446484 |
|---|---|
| Mm.1025 | |
| Rn.10867 |
| KEGG pathway | Prion disease |
|---|
| GO Cellular Component | nucleus |
|---|
| Cell Localization | Nucleus |
|---|
| Pathway | FGF7-FGFR2 |
|---|---|
| FGF7-GPC1 | |
| IL1B-HLA-DRB1 | |
| IL1B-IL1R1 | |
| IL1B-IL1RAP | |
| IL1B-IL6R | |
| DuPont 2 | |
| DuPont 4 | |
| Volcano 2 | |
| PPAR all | |
| PPARgamma |
| GO Biological Process | transcription from Pol II promoter |
|---|---|
| regulation of transcription, DNA-dependent | |
| transcription | |
| transcription from RNA polymerase II promoter |
| Group | Transcription factors |
|---|
| MGI ID | 108420 |
|---|
| Swiss-Prot Accession | Q16236 |
|---|
| OMIM ID | 600492 |
|---|
| Source | Curated |
|---|